Chromothripsis: how does such a catastrophic event impact human reproduction?
نویسندگان
چکیده
منابع مشابه
Chromothripsis: how does such a catastrophic event impact human reproduction?
The recent discovery of a new kind of massive chromosomal rearrangement, baptized chromothripsis (chromo for chromosomes, thripsis for shattering into pieces), greatly modifies our understanding of molecular mechanisms implicated in the repair of DNA damage and the genesis of complex chromosomal rearrangements. Initially described in cancers, and then in constitutional rearrangements, chromothr...
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متن کاملChromothripsis
to determine whether C is part of the mechanism by which A contributes to B. Biologists use convergency and consistency amongst these experiments to judge the strength of any causal assertion. Therefore, in research maps convergency and consistency amongst results increases the score assigned to each edge, while contradictory results have the opposite effect. By selecting any one edge in a part...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2014
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/deu003